This is the first post of an abstract series, and a taster of one of the topics at the Eagle Symposium 2015 kindly provided by Philippe Sanseau, Head of Computational Biology at GSK addressing the subject of "Bioinformatics and Drug Discovery: A Good Combination?"
Abstract: "Modern biology is often associated with the generation of very large and diverse data sets. In the context of basic research the role of bioinformatics in managing and analysing this data is largely well recognised. In the pharmaceutical industry picking targets and pathways to modulate with small molecules or biologicals presents different challenges. Many steps are necessary in preclinical and clinical research before an effective and safe medicine could be delivered to patients. I will illustrate what impact bioinformatics can have in the discovery and development of new medicines and what strategic and scientific approaches we have been using."
Speaker's Bio: Philippe Sanseau received his PhD from the University of Rennes in France. He completed his post-doctoral training at the Imperial Cancer Research Fund in London (now Cancer Research UK) with a focus on Immunogenetics. He joined GlaxoSmithKline (GSK) to work initially in the Genetics and Genomics Departments, and since 2001 has held various senior roles in bioinformatics and computational biology. Since 2009 he has been leading GSK's Computational Biology Department with a team of scientists located in the UK and US.
GSK's Computational Biology Department works on multiple therapeutic areas supporting projects at all phases of the drug discovery and development pipeline using diverse bioinformatics approaches applied to biomedical internal and external data. The Computational Biology Department maintains a strong scientific innovation agenda as demonstrated by:
(i) activities in drug repositioning, systems approaches, microbiome analyses,
(ii) developing a network of academic collaborators and
(iii) maintaining a strong publication record.
Philippe is a member of several international advisory boards as well as various UK and international funding committees.
Eagle Symposium 2015: Eagle Genomics organises an annual industry symposium for the active engagement of scientific professionals in the promotion of innovation and advancement in genomics, bioinformatics, and computational biology to help address global issues. The Eagle Symposium 2015 builds on the theme "Bridging Biology and Informatics for R&D Innovation", taking place on 23 March 2015 at the European Bioinformatics Institute (EBI), Wellcome Trust Genome Campus in Hinxton, Cambridge, UK.